Exfoliation (pseudoexfoliation) Syndrome is characterized by the fibrillar deposits in the anterior segment of the eye. The deposits have been found on and in the subconjunctival tissue, pupillary margin, ciliary epithelium, lens epithelium, lens capsule, iris pigment epithelium, trabecular meshwork, cornea, zonules, orbital soft tissues, iris stroma and iris blood vessels. These deposits have also been found elsewhere in the body, including in the skin, heart, lungs, liver, kidneys, and elsewhere. The disease may be bilateral and asymmetric. It has been associated with myocardial infarction, cerebrovascular events and systemic hypertension